Gene

tfb1m

ID

ZDB-GENE-060929-1010

Name

transcription factor B1, mitochondrial

Symbol

tfb1m Nomenclature History

Previous Names

im:7151479
zgc:153625 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable mitochondrial transcription factor activity and rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation and transcription initiation at mitochondrial promoter. Predicted to act upstream of or within methylation and rRNA modification. Predicted to be active in mitochondrial matrix. Orthologous to human TFB1M (transcription factor B1, mitochondrial).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7151479 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tfb1m Human Ortholog

No data available

Associated With tfb1m Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR020598	Ribosomal RNA adenine methylase transferase, N-terminal
Family	IPR001737	Ribosomal RNA adenine methyltransferase KsgA/Erm
Family	IPR011530	Ribosomal RNA adenine dimethylase
Homologous_superfamily	IPR023165	rRNA adenine dimethylase-like, C-terminal
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily

Domain Details Per Protein

Protein	Length	Ribosomal RNA adenine dimethylase	Ribosomal RNA adenine methylase transferase, N-terminal	Ribosomal RNA adenine methyltransferase KsgA/Erm	rRNA adenine dimethylase-like, C-terminal	S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:A0A8M9P924 InterPro	354
UniProtKB:A0A8M2BH57 InterPro	349
UniProtKB:A0A8M9PNX5 InterPro	238
UniProtKB:Q08C48 InterPro	269
UniProtKB:A0A8M9PEE3 InterPro	314

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tfb1m-201 (1) Ensembl	Ensembl	1,711 nt	Select Tool ZFIN BLAST
mRNA	tfb1m-202 (1) Ensembl	Ensembl	879 nt	Select Tool ZFIN BLAST
mRNA	tfb1m-203 (1) Ensembl	Ensembl	1,372 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations