ZFIN is now using GRCz12tu for Genomic Data
Gene
fgf10b
- ID
- ZDB-GENE-060828-1
- Name
- fibroblast growth factor 10b
- Symbol
- fgf10b Nomenclature History
- Previous Names
-
- fgf25 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable chemoattractant activity; growth factor activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within several processes, including liver development; otic vesicle development; and pancreas development. Predicted to be active in cytoplasm and extracellular space. Is expressed in digestive system; lateral line system; mesoderm; pronephros; and tail bud. Human ortholog(s) of this gene implicated in aplasia of lacrimal and salivary glands and lacrimoauriculodentodigital syndrome 3. Orthologous to human FGF10 (fibroblast growth factor 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| aplasia of lacrimal and salivary glands | Alliance | Aplasia of lacrimal and salivary glands | 180920 |
| lacrimoauriculodentodigital syndrome 3 | Alliance | LADD syndrome 3 | 620193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|---|
| UniProtKB:Q1XG75 | InterPro | 187 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fgf10b-201
(1)
|
Ensembl | 1,739 nt | ||
| mRNA |
fgf10b-202
(1)
|
Ensembl | 564 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers