ZFIN ID: ZDB-GENE-060825-55
Gene Name: hes family bHLH transcription factor 2, tandem duplicate 2
Gene Symbol: hes2.2    Nomenclature History

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Previous Names: Hes2b (1), zgc:153398

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to localize to nucleus. Is expressed in eye; gill; heart; and liver. Orthologous to human HES2 (hes family bHLH transcription factor 2).
Genome Resources: Alliance (1),  Gene:751634 (1),  Ensembl(GRCz11):ENSDARG00000068168 (2)
GENE EXPRESSION
All Expression Data: Fig. S6 from Zhou et al., 2012
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hes2.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hes2.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hes2.2-201 (1)    Ensembl 1090
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hes2.2 No data available
MARKER RELATIONSHIPS
hes2.2 Contained in: [BAC] CH211-122N14 (1)
hes2.2 Encodes: [cDNA] MGC:153398 (1), MGC:192059 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045353 (1) 1111 nt
Genomic GenBank:CR954167 (1) 160594 nt
Select Tool
Polypeptide UniProtKB:B0V2G5 (1) 191 aa
Sequence Information (all 14)
ORTHOLOGY for hes2.2 ( Chr: 8 )
CITATIONS (18)