Gene

spi1a

ID
ZDB-GENE-060825-351
Name
Spi-1 proto-oncogene a
Symbol
spi1a Nomenclature History
Previous Names
  • spi1l (1)
  • zgc:152991
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in regulation of myeloid leukocyte differentiation. Predicted to localize to nucleus. Is expressed in anterior lateral plate mesoderm; intermediate cell mass of mesoderm; kidney; rostral blood island; and yolk. Orthologous to human SPI1 (Spi-1 proto-oncogene) and SPIB (Spi-B transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Bukrinsky et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spi1a Human Ortholog
No data available
Associated With spi1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000418 Ets domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Ets domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:B2GSA7 247
UniProtKB:F1QFB6 257
UniProtKB:Q0P4E9 247
UniProtKB:B3GEA5 252
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations