Gene
tefm
- ID
- ZDB-GENE-060825-345
- Name
- transcription elongation factor, mitochondrial
- Symbol
- tefm Nomenclature History
- Previous Names
-
- zgc:153083
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA polymerase processivity factor activity and transcription elongation factor activity. Predicted to be involved in mitochondrial transcription and positive regulation of mitochondrial transcription. Predicted to act upstream of or within transcription elongation by mitochondrial RNA polymerase and translational elongation. Predicted to be located in mitochondrial matrix. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrial nucleoid. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human TEFM (transcription elongation factor, mitochondrial).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Combined oxidative phosphorylation deficiency 58 | 620451 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ribonuclease H superfamily | RuvA domain 2-like | Transcription elongation factor, mitochondrial |
|---|---|---|---|---|---|
| UniProtKB:Q0P4D6 | InterPro | 363 | |||
| UniProtKB:A0A8M2BDK3 | InterPro | 317 | |||
| UniProtKB:A0A8M6Z6R6 | InterPro | 354 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available