Gene

elp6

ID

ZDB-GENE-060825-249

Name

elongator acetyltransferase complex subunit 6

Symbol

elp6 Nomenclature History

Previous Names

si:dkey-77n11.4
tmem103
zgc:153530

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to be involved in positive regulation of cell migration. Predicted to act upstream of or within tRNA wobble uridine modification. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. Orthologous to human ELP6 (elongator acetyltransferase complex subunit 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With elp6 Human Ortholog

No data available

Associated With elp6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR018627	Elongator complex protein 6
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

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Domain Details Per Protein

Protein	Additional Resources	Length	Elongator complex protein 6	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q0P424	InterPro	264

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 16

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	elp6-202 (1) Ensembl	Ensembl	1,021 nt	Select Tool ZFIN BLAST
mRNA	elp6-203 (1) Ensembl	Ensembl	4,498 nt	Select Tool ZFIN BLAST
ncRNA	elp6-002 (1) Ensembl	Ensembl	529 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-77N11	AL929190	ZFIN Curated Data
Encodes	cDNA	MGC:153530	BC122319	ZFIN Curated Data
Encodes	cDNA	MGC:174607	BC152243	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001103142 (1)	1257 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:AL929190 (1)	150892 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q0P424 (1)	264 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	ELP6	3	Ensembl:ENSG00000163832 Gene:54859 HGNC:25976 OMIM:615020	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Elp6	9	Ensembl:ENSMUSG00000054836 Gene:72341 MGI:1919349	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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