Gene
zgc:153383
- ID
- ZDB-GENE-060825-178
- Name
- zgc:153383
- Symbol
- zgc:153383 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Orthologous to human FAM177A1 (family with sequence similarity 177 member A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-zgc:153383 | (2) | |
| CRISPR2-zgc:153383 | (2) |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR028260 | FAM177 family |
Domain Details Per Protein
| Protein | Additional Resources | Length | FAM177 family |
|---|---|---|---|
| UniProtKB:A0A8M6Z2Q7 | InterPro | 172 | |
| UniProtKB:A0A8M2BFI5 | InterPro | 205 | |
| UniProtKB:A0A8M1N9K0 | InterPro | 152 | |
| UniProtKB:A0A8M9P2R9 | InterPro | 110 | |
| UniProtKB:Q0P461 | InterPro | 134 | |
| UniProtKB:A0A8M2BFJ3 | InterPro | 162 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:153383-201
(1)
|
Ensembl | 699 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-97L20 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:153383 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045461 (1) | 678 nt | ||
| Genomic | GenBank:BX005367 (2) | 243709 nt | ||
| Polypeptide | UniProtKB:A0A8M2BFI5 (1) | 205 aa |
No data available
- Kohler, J.N., Legro, N.R., Baldridge, D., Shin, J., Bowman, A., Ugur, B., Jackstadt, M.M., Shriver, L.P., Patti, G.J., Zhang, B., Feng, W., McAdow, A.R., Goddard, P., Ungar, R.A., Jensen, T., Smith, K.S., Fresard, L., Alvarez, R., Bonner, D., Reuter, C.M., McCormack, C., Kravets, E., Marwaha, S., Holt, J.M., Undiagnosed Diseases Network, Worthey, E., Ashley, E.A., Montgomery, S.B., Fisher, P., Postlethwait, J., De Camilli, P., Solnica-Krezel, L., Bernstein, J.A., Wheeler, M.T. (2024) Loss of function of FAM177A1, a Golgi complex localized protein, causes a novel neurodevelopmental disorder. Genetics in medicine : official journal of the American College of Medical Genetics. 26(9):101166
- Ugur, B., Schueder, F., Shin, J., Hanna, M.G., Wu, Y., Leonzino, M., Su, M., McAdow, A.R., Wilson, C., Postlethwait, J., Solnica-Krezel, L., Bewersdorf, J., De Camilli, P. (2024) VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1. The Journal of cell biology. 223(12):
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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