Gene

kti12

ID

ZDB-GENE-060825-174

Name

KTI12 chromatin associated homolog

Symbol

kti12 Nomenclature History

Previous Names

si:dkey-77f17.5
zgc:153393 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity. Predicted to be involved in tRNA wobble uridine modification. Orthologous to human KTI12 (KTI12 chromatin associated homolog).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa18293	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With kti12 Human Ortholog

No data available

Associated With kti12 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR013641	Protein KTI12/L-seryl-tRNA(Sec) kinase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

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Domain Details Per Protein

Protein	Additional Resources	Length	P-loop containing nucleoside triphosphate hydrolase	Protein KTI12/L-seryl-tRNA(Sec) kinase
UniProtKB:Q0P457	InterPro	275

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 18

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	kti12-201 (1) Ensembl	Ensembl		1,884 nt	Select Tool ZFIN BLAST
mRNA	kti12-202 (1) Ensembl	Ensembl		1,030 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-77F17	AL935332	ZFIN Curated Data
Encodes	cDNA	MGC:153393	BC122265	ZFIN Curated Data
Encodes	cDNA	MGC:191799	BC164624	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001126418 (1)	1030 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CT967325 (1)	267826 nt	Select Tool MegaBLAST
Polypeptide	UniProtKB:Q0P457 (1)	275 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	KTI12	1	Ensembl:ENSG00000198841 Gene:112970 HGNC:25160	Amino acid sequence comparison (1)
Mouse	Kti12	4	Ensembl:ENSMUSG00000073775 Gene:100087 MGI:1923547	Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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