Gene
chst6
- ID
- ZDB-GENE-060810-74
- Name
- carbohydrate sulfotransferase 6
- Symbol
- chst6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity. Acts upstream of or within cornea development in camera-type eye and regulation of bone development. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to several human genes including CHST5 (carbohydrate sulfotransferase 5) and CHST6 (carbohydrate sulfotransferase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7157221 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Basol et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| macular corneal dystrophy | Alliance | Macular corneal dystrophy | 217800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Carbohydrate sulfotransferase | Gal/GlcNAc/GalNAc Sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|---|
| UniProtKB:B3DIF5 | InterPro | 398 | ||||
| UniProtKB:A0A8M2BA60 | InterPro | 435 |
Interactions and Pathways
No data available
Plasmids
No data available