ZFIN is now using GRCz12tu for Genomic Data
Gene
chst6
- ID
- ZDB-GENE-060810-74
- Name
- carbohydrate sulfotransferase 6
- Symbol
- chst6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity. Acts upstream of or within cornea development in camera-type eye and regulation of bone development. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network. Is expressed in brain; head; and trunk. Used to study macular corneal dystrophy. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to several human genes including CHST5 (carbohydrate sulfotransferase 5) and CHST6 (carbohydrate sulfotransferase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7157221 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Basol et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| macular corneal dystrophy | Alliance | Macular corneal dystrophy | 217800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Carbohydrate sulfotransferase | Gal/GlcNAc/GalNAc Sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|---|
| UniProtKB:B3DIF5 | InterPro | 398 | ||||
| UniProtKB:A0A8M2BA60 | InterPro | 435 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers