Gene

mief1

ID

ZDB-GENE-060810-64

Name

mitochondrial elongation factor 1

Symbol

mief1 Nomenclature History

Previous Names

im:7156228
smcr7a
smcr7l (1)
zgc:162279 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have nucleotide binding activity. Predicted to be involved in positive regulation of mitochondrial fission and positive regulation of protein targeting to membrane. Predicted to localize to mitochondrial outer membrane. Orthologous to several human genes including MIEF1 (mitochondrial elongation factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7156228 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mief1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Optic atrophy 14	620550

Associated With mief1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR046906	Mab-21-like, HhH/H2TH-like domain
Domain	IPR049097	Mitochondrial dynamics protein MID51-like, C-terminal domain
Family	IPR024810	MAB21L/Cyclic GMP-AMP synthase-like receptor
Family	IPR045909	Mitochondrial dynamics protein MID49/MID51