Gene

ehd4

ID

ZDB-GENE-060810-22

Name

EH-domain containing 4

Symbol

ehd4 Nomenclature History

Previous Names

im:7147183

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; GTP binding activity; and calcium ion binding activity. Predicted to be involved in several processes, including cilium assembly; endocytic recycling; and protein localization to plasma membrane. Predicted to localize to several cellular components, including cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Is expressed in cardiovascular system; presumptive telencephalon; and telencephalon. Orthologous to human EHD4 (EH domain containing 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147183 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ehd4 Human Ortholog

No data available

Associated With ehd4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR000261	EH domain
Domain	IPR002048	EF-hand domain
Domain	IPR030381	Dynamin-type guanine nucleotide-binding (G) domain
Domain	IPR031692	EH domain-containing protein, N-terminal
Domain	IPR040990	Domain of unknown function DUF5600
Domain	IPR045063	Dynamin, N-terminal
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase