Gene

gfer

ID
ZDB-GENE-060810-186
Name
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
Symbol
gfer Nomenclature History
Previous Names
  • alr (1)
  • hepatopoietin (1)
  • im:7163713
  • zgc:162159
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits flavin-linked sulfhydryl oxidase activity and identical protein binding activity. Involved in heart development and liver development. Localizes to mitochondrion. Is expressed in several structures, including fin; gill; head; liver and biliary system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Orthologous to human GFER (growth factor, augmenter of liver regeneration).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Li et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gfer Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopathy, mitochondrial progressive, with congenital cataract and developmental delay 613076
Associated With gfer Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017905 ERV/ALR sulfhydryl oxidase domain
Family IPR039799 Sulfhydryl oxidase ALR/ERV
Homologous_superfamily IPR036774 ERV/ALR sulfhydryl oxidase domain superfamily
Domain Details Per Protein
Protein Length ERV/ALR sulfhydryl oxidase domain ERV/ALR sulfhydryl oxidase domain superfamily Sulfhydryl oxidase ALR/ERV
UniProtKB:A4QNU9 191
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations