Gene
gfer
- ID
- ZDB-GENE-060810-186
- Name
- growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
- Symbol
- gfer Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Enables flavin-linked sulfhydryl oxidase activity and identical protein binding activity. Acts upstream of or within heart development and liver development. Located in mitochondrion. Is expressed in several structures, including fin; gill; head; liver and biliary system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Orthologous to human GFER (growth factor, augmenter of liver regeneration).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7163713 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Li et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopathy, mitochondrial progressive, with congenital cataract and developmental delay | 613076 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ERV/ALR sulfhydryl oxidase domain | ERV/ALR sulfhydryl oxidase domain superfamily | Sulfhydryl oxidase ALR/ERV |
|---|---|---|---|---|
|
UniProtKB:A4QNU9
|
191 |
Interactions and Pathways
No data available
Plasmids
No data available