Gene

itgb1a

ID

ZDB-GENE-060803-2

Name

integrin, beta 1a

Symbol

itgb1a Nomenclature History

Previous Names

beta1-1 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Exhibits fibronectin binding activity and protein heterodimerization activity. Involved in positive regulation of sprouting angiogenesis. Predicted to localize to cell surface; focal adhesion; and integrin complex. Is expressed in several structures, including cardiovascular system; integument; liver; periderm; and pleuroperitoneal region. Orthologous to human ITGB1 (integrin subunit beta 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With itgb1a Human Ortholog

No data available

Associated With itgb1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002369	Integrin beta subunit, VWA domain
Domain	IPR012896	Integrin beta subunit, tail
Domain	IPR013111	EGF-like domain, extracellular
Domain	IPR014836	Integrin beta subunit, cytoplasmic domain
Domain	IPR016201	PSI domain
Domain	IPR033760	Integrin beta N-terminal
Domain	IPR040622	Integrin beta, epidermal growth factor-like domain 1
Family	IPR015812	Integrin beta subunit
Homologous_superfamily	IPR032695	Integrin domain superfamily
Homologous_superfamily	IPR036349	Integrin beta tail domain superfamily
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily