ZFIN ID: ZDB-GENE-060724-1
Gene Name: interleukin 12a
Gene Symbol: il12a    Nomenclature History

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Previous Name: IL-12p35 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Involved in response to exogenous dsRNA and response to lipopolysaccharide. Is expressed in intestine. Human ortholog(s) of this gene implicated in hepatitis C; hepatocellular carcinoma; and primary biliary cirrhosis. Orthologous to human IL12A (interleukin 12A).
Genome Resources: Alliance (1),  Gene:445410 (1),  Ensembl(GRCz11):ENSDARG00000038878 (1)
GENE EXPRESSION
All Expression Data: 13 figures from 7 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb420 Small Deletion Exon 3 Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-il12a 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH il12a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH il12a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to exogenous dsRNA (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA il12a-201 (1)    Ensembl 949
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM il12a No data available
MARKER RELATIONSHIPS
il12a Contained in: [BAC] DKEYP-97B10 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001007107 (1) 946 nt
Genomic GenBank:CT027672 (1) 120126 nt
Select Tool
Polypeptide UniProtKB:Q6F3R0 (1) 204 aa
Sequence Information (all 9)
ORTHOLOGY for il12a ( Chr: 15 )
CITATIONS (47)