Gene
lrata
- ID
- ZDB-GENE-060720-1
- Name
- lecithin retinol acyltransferase a
- Symbol
- lrata Nomenclature History
- Previous Names
-
- lrat
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have phosphatidylcholine-retinol O-acyltransferase activity. Predicted to be involved in retinol metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Is expressed in head; liver; pleuroperitoneal region; and visual system. Orthologous to human LRAT (lecithin retinol acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leber congenital amaurosis 14 | Alliance | Leber congenital amaurosis 14 | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinal dystrophy, early-onset severe | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinitis pigmentosa, juvenile | 613341 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Lecithin retinol acyltransferase | LRAT domain |
|---|---|---|---|
|
UniProtKB:Q6DC51
|
232 | ||
|
UniProtKB:F1Q7T8
|
225 |
Interactions and Pathways
No data available
Plasmids
No data available