Gene

tbc1d1

ID

ZDB-GENE-060710-1

Name

TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1

Symbol

tbc1d1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity and Rab GTPase binding activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Orthologous to human TBC1D1 (TBC1 domain family member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tbc1d1 Human Ortholog

No data available

Associated With tbc1d1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000195	Rab-GAP-TBC domain
Domain	IPR006020	PTB/PI domain
Domain	IPR021785	Domain of unknown function DUF3350
Family	IPR050302	Rab GTPase-activating TBC domain-containing protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035969	Rab-GAP-TBC domain superfamily

Domain Details Per Protein

Protein	Length	Domain of unknown function DUF3350	PH-like domain superfamily	PTB/PI domain	Rab-GAP-TBC domain	Rab-GAP-TBC domain superfamily	Rab GTPase-activating TBC domain-containing protein
UniProtKB:A0A8N7UT15 InterPro	1203
UniProtKB:A0A8M9QE63 InterPro	1236
UniProtKB:A0A8M2BFN8 InterPro	1276
UniProtKB:A0A8M9Q8V8 InterPro	1115
UniProtKB:A0A8M2BGB4 InterPro	1130

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tbc1d1-201 (1) Ensembl	Ensembl	5,011 nt	Select Tool
mRNA	tbc1d1-204 (1) Ensembl	Ensembl	4,891 nt	Select Tool
mRNA	tbc1d1-205 (1) Ensembl	Ensembl	4,792 nt	Select Tool
mRNA	tbc1d1-206 (1) Ensembl	Ensembl	6,261 nt	Select Tool ZFIN BLAST
mRNA	tbc1d1-207 (1) Ensembl	Ensembl	3,555 nt	Select Tool ZFIN BLAST
mRNA	tbc1d1-208 (1) Ensembl	Ensembl	6,162 nt	Select Tool ZFIN BLAST
ncRNA	tbc1d1-003 (1) Ensembl	Ensembl	959 nt	Select Tool
ncRNA	tbc1d1-004 (1) Ensembl	Ensembl	399 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations