Gene
plcb4b
- ID
- ZDB-GENE-060627-1
- Name
- phospholipase C, beta 4b
- Symbol
- plcb4b Nomenclature History
- Previous Names
-
- plcb4
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable calcium ion binding activity and phosphatidylinositol phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Is expressed in spinal cord. Orthologous to human PLCB4 (phospholipase C beta 4).
- Genome Resources
-
- Alliance (1)
- Gene:407700 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain |
| Domain | IPR014815 | Phospholipase C-beta, C-terminal domain |
| Domain | IPR037862 | PLC-beta, PH domain |
| Domain | IPR053945 | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Family | IPR016280 | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR042531 | Phospholipase C-beta, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | EF-hand domain pair | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain | Phosphoinositide phospholipase C family | Phospholipase C-beta, C-terminal domain | Phospholipase C-beta, C-terminal domain superfamily | Phospholipase C, phosphatidylinositol-specific, Y domain | PLC-beta, PH domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TKB8 | InterPro | 1343 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance