Gene
adgrb1a
- ID
- ZDB-GENE-060607-12
- Name
- adhesion G protein-coupled receptor B1a
- Symbol
- adgrb1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and engulfment of apoptotic cell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; and negative regulation of angiogenesis. Predicted to be located in membrane. Predicted to be active in dendrite; plasma membrane; and postsynaptic density. Is expressed in muscle; nervous system; and testis. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR032471 | GAIN domain, N-terminal |
| Domain | IPR043838 | Adhesion G protein-coupled receptor B, N-terminal domain |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR008077 | GPCR, family 2, brain-specific angiogenesis inhibitor |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Adhesion G protein-coupled receptor B, N-terminal domain | GAIN domain, N-terminal | GAIN domain superfamily | GPCR, family 2, brain-specific angiogenesis inhibitor | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPS motif | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AQX5 | InterPro | 1598 | |||||||||||
| UniProtKB:A0A8M9NZT5 | InterPro | 1514 | |||||||||||
| UniProtKB:A0A8M3AQX9 | InterPro | 1554 | |||||||||||
| UniProtKB:A0A2R8PX08 | InterPro | 1610 | |||||||||||
| UniProtKB:A0A8M9PK78 | InterPro | 1519 | |||||||||||
| UniProtKB:A0A8M3ATQ5 | InterPro | 1605 | |||||||||||
| UniProtKB:A0A8M9PDS9 | InterPro | 1575 | |||||||||||
| UniProtKB:A0A8M3B1X9 | InterPro | 1547 | |||||||||||
| UniProtKB:E7F9S0 | InterPro | 1529 | |||||||||||
| UniProtKB:A0A8M3AJE0 | InterPro | 1577 | |||||||||||
| UniProtKB:A0A8M3AIF0 | InterPro | 1549 | |||||||||||
| UniProtKB:A0A8M9P8H3 | InterPro | 1261 | |||||||||||
| UniProtKB:A0A8M3B1X6 | InterPro | 1580 | |||||||||||
| UniProtKB:A0A2R8PVQ8 | InterPro | 1585 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgrb1a-201
(1)
|
Ensembl | 8,537 nt | ||
| mRNA |
adgrb1a-203
(1)
|
Ensembl | 3,497 nt | ||
| mRNA |
adgrb1a-204
(1)
|
Ensembl | 8,780 nt | ||
| mRNA |
adgrb1a-205
(1)
|
Ensembl | 8,705 nt | ||
| ncRNA |
adgrb1a-002
(1)
|
Ensembl | 1,391 nt |
Interactions and Pathways
No data available
Plasmids
No data available