Gene

arhgef28a

ID
ZDB-GENE-060531-28
Name
Rho guanine nucleotide exchange factor (GEF) 28a
Symbol
arhgef28a Nomenclature History
Previous Names
  • arhgef28 (1)
  • rgnef (1)
  • p190RhoGEF (1)
  • si:ch211-1o14.5 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in Golgi organization; cell-matrix adhesion; and muscle tissue morphogenesis. Is expressed in ball; head; notochord; somite; and trunk. Orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Cao et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef28a Human Ortholog
No data available
Associated With arhgef28a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR037819 ARHGEF28, PH domain
Domain IPR041020 ARHGEF1-like, PH domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Domain Details Per Protein
Protein Length ARHGEF1-like, PH domain ARHGEF28, PH domain Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily Pleckstrin homology domain Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
UniProtKB:F6P6M2 1753
UniProtKB:F1R083 981
UniProtKB:A0A2R8PYT3 1600
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations