Gene
mark4a
- ID
- ZDB-GENE-060531-156
- Name
- MAP/microtubule affinity-regulating kinase 4a
- Symbol
- mark4a Nomenclature History
- Previous Names
-
- sb:eu746
- si:dkey-85k8.8
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to localize to cytoplasm. Orthologous to human MARK4 (microtubule affinity regulating kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu746 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001772 | Kinase associated domain 1 (KA1) |
| Domain | IPR015940 | Ubiquitin-associated domain |
| Domain | IPR049508 | Serine/threonine-protein kinase MARK 1-4, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR028375 | KA1 domain/Ssp2, C-terminal |
Domain Details Per Protein
| Protein | Length | KA1 domain/Ssp2, C-terminal | Kinase associated domain 1 (KA1) | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase MARK 1-4, catalytic domain | Ubiquitin-associated domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BCS1
|
762 | ||||||||
|
UniProtKB:A0A8M2BCN5
|
758 | ||||||||
|
UniProtKB:A0A8M9Q9J1
|
693 | ||||||||
|
UniProtKB:A0A8M9QER0
|
697 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mark4a-201
(1)
|
Ensembl | 2,211 nt | ||
| mRNA |
mark4a-202
(1)
|
Ensembl | 2,330 nt |
Interactions and Pathways
No data available
Plasmids
No data available