Gene
mark4a
- ID
- ZDB-GENE-060531-156
- Name
- MAP/microtubule affinity-regulating kinase 4a
- Symbol
- mark4a Nomenclature History
- Previous Names
-
- sb:eu746
- si:dkey-85k8.8
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm. Orthologous to human MARK4 (microtubule affinity regulating kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu746 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001772 | Kinase associated domain 1 (KA1) |
| Domain | IPR015940 | Ubiquitin-associated domain |
| Domain | IPR049508 | Serine/threonine-protein kinase MARK 1-4, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR028375 | KA1 domain/Ssp2, C-terminal |
Domain Details Per Protein
| Protein | Length | KA1 domain/Ssp2, C-terminal | Kinase associated domain 1 (KA1) | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase MARK 1-4, catalytic domain | Ubiquitin-associated domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BCS1
|
762 | ||||||||
|
UniProtKB:A0A8M2BCN5
|
758 | ||||||||
|
UniProtKB:A0A8M9Q9J1
|
693 | ||||||||
|
UniProtKB:A0A8M9QER0
|
697 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mark4a-201
(1)
|
Ensembl | 2,211 nt | ||
| mRNA |
mark4a-202
(1)
|
Ensembl | 2,330 nt |
Interactions and Pathways
No data available
Plasmids
No data available