Gene
sptbn4a
- ID
- ZDB-GENE-060531-133
- Name
- spectrin, beta, non-erythrocytic 4a
- Symbol
- sptbn4a Nomenclature History
- Previous Names
-
- si:dkey-27p18.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within actin filament capping. Predicted to be active in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Human ortholog(s) of this gene implicated in hereditary pyropoikilocytosis; hereditary spherocytosis; and hereditary spherocytosis type 3. Orthologous to human SPTA1 (spectrin alpha, erythrocytic 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology domain, spectrin-type | Spectrin/alpha-actinin | Spectrin repeat |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1PSP0
|
1409 | |||||
|
UniProtKB:A0A8M9Q1I6
|
1168 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-27p18.5-201
(1)
|
Ensembl | 4,239 nt |
Interactions and Pathways
No data available
Plasmids
No data available