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Gene

ptger4b

ID
ZDB-GENE-060531-102
Name
prostaglandin E receptor 4 (subtype EP4) b
Symbol
ptger4b Nomenclature History
Previous Names
  • ep4b (1)
  • PRS5 (1)
  • si:dkey-204l11.6
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables prostaglandin E receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gill; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptger4b Human Ortholog
No data available
Associated With ptger4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001244 Prostaglandin DP receptor
Family IPR001758 Prostanoid EP4 receptor
Family IPR008365 Prostanoid receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Prostaglandin DP receptor Prostanoid EP4 receptor Prostanoid receptor
UniProtKB:A0A2R8PYV0 418
UniProtKB:A3QK20 497
UniProtKB:A0A2R8RL91 462
UniProtKB:A0A2R8RQ84 456
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations