Gene

cfap251

ID
ZDB-GENE-060526-328
Name
cilia and flagella associated protein 251
Symbol
cfap251 Nomenclature History
Previous Names
  • si:dkey-65b12.4 (1)
  • wdr66
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Involved in neutrophil differentiation and thrombocyte differentiation. Predicted to localize to sperm flagellum. Human ortholog(s) of this gene implicated in male infertility. Orthologous to human WDR66 (WD repeat domain 66).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Bielczyk-MaczyƄska et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cfap251 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spermatogenic failure 33 Alliance Spermatogenic failure 33 618152
Associated With cfap251 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length EF-hand domain pair Quinoprotein alcohol dehydrogenase-like superfamily WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M9PR50 917
UniProtKB:A0A2R8RY46 963
UniProtKB:A0A8M9Q1S6 537
UniProtKB:F1Q8Y1 963
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations