Gene
alkbh2
- ID
- ZDB-GENE-060526-327
- Name
- alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
- Symbol
- alkbh2 Nomenclature History
- Previous Names
-
- si:dkey-65b12.2
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable broad specificity oxidative DNA demethylase activity; cytosine C-5 DNA demethylase activity; and ferrous iron binding activity. Predicted to be involved in DNA alkylation repair. Predicted to act upstream of or within DNA repair. Orthologous to human ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005123 | Oxoglutarate/iron-dependent dioxygenase domain |
| Domain | IPR027450 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like |
| Family | IPR032852 | DNA oxidative demethylase ALKBH2 |
| Homologous_superfamily | IPR037151 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha-ketoglutarate-dependent dioxygenase AlkB-like | Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily | DNA oxidative demethylase ALKBH2 | Oxoglutarate/iron-dependent dioxygenase domain |
|---|---|---|---|---|---|---|
| UniProtKB:A3QK41 | InterPro | 258 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
alkbh2-201
(1)
|
Ensembl | 999 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-65B12 | ZFIN Curated Data |
1 - 1 of 1
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001256684 (1) | |||
| Genomic | GenBank:CR931763 (1) | 186739 nt | ||
| Polypeptide | UniProtKB:A3QK41 (1) | 258 aa |