Gene

ube3b

ID
ZDB-GENE-060526-231
Name
ubiquitin protein ligase E3B
Symbol
ube3b Nomenclature History
Previous Names
  • si:dkey-189p24.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Human ortholog(s) of this gene implicated in Kaufman oculocerebrofacial syndrome. Orthologous to human UBE3B (ubiquitin protein ligase E3B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ube3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Kaufman oculocerebrofacial syndrome Alliance Kaufman oculocerebrofacial syndrome 244450
Associated With ube3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR000569 HECT domain
Homologous_superfamily IPR035983 HECT, E3 ligase catalytic domain
Domain Details Per Protein
Protein Length HECT domain HECT, E3 ligase catalytic domain IQ motif, EF-hand binding site
UniProtKB:A2BGM8 1069
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations