ZFIN ID: ZDB-GENE-060526-217
Gene Name: ataxin 2
Gene Symbol: atxn2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkey-165i4.1 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in regulation of cytoplasmic mRNA processing body assembly and stress granule assembly. Predicted to localize to cytoplasmic stress granule. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Orthologous to human ATXN2 (ataxin 2).
Genome Resources: Alliance (1),  Gene:569210 (1),  Ensembl(GRCz11):ENSDARG00000052897 (1)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atxn2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
late onset Parkinson's disease Alliance {Parkinson disease, late-onset, susceptibility to} 168600
spinocerebellar ataxia type 2 Alliance Spinocerebellar ataxia 2 183090
{Amyotrophic lateral sclerosis, susceptibility to, 13} 183090
DISEASE ASSOCIATED WITH atxn2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of cytoplasmic mRNA processing body assembly (more)
Cellular Component cytoplasmic stress granule (more)
Molecular Function RNA binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atxn2-201 (1)    Ensembl 4204
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atxn2 No data available
MARKER RELATIONSHIPS
atxn2 Contained in: [BAC] DKEY-165I4 (1) (order this), DKEYP-30C3 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001128349 (1)
Genomic GenBank:CR753867 (1) 125222 nt
Select Tool
Polypeptide UniProtKB:A2CF31 (1) 1112 aa
Sequence Information (all 31)
ORTHOLOGY for atxn2 ( Chr: 5 )
CITATIONS (17)