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ZIRC
ZFIN ID: ZDB-GENE-060526-211
Gene Name: bone morphogenetic protein 10
Gene Symbol: bmp10    Nomenclature History

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Previous Names: bmp10b (1), si:dkey-13n15.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have cytokine activity and transforming growth factor beta receptor binding activity. Involved in artery development. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is expressed in pericardial region. Orthologous to human BMP10 (bone morphogenetic protein 10).
Genome Resources: Alliance (1),  Gene:562533 (1),  Ensembl(GRCz11):ENSDARG00000061769 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7560 Point Mutation Unknown Missense ENU
sa16377 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20384 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33575 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40400 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bmp10 N/A 1
    MO2-bmp10 N/A 1
    DISEASE ASSOCIATED WITH bmp10 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bmp10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process artery development (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bmp10-201 (1)    Ensembl 1458
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bmp10 No data available
    MARKER RELATIONSHIPS
    bmp10 Contained in: [BAC] DKEY-13N15 (1) (order this)
    bmp10 Encodes: [cDNA] MGC:195288 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001130600 (1) 1529 bp
    Genomic GenBank:BX470224 (1) 244492 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A2BGK2 (1) 485 aa
    Sequence Clusters UniGene:114884 (1)
    Sequence Information (all 10)
    ORTHOLOGY for bmp10 ( Chr: 5 )
    CITATIONS (27)