ZFIN is now using GRCz12tu for Genomic Data
Gene
tpcn1
- ID
- ZDB-GENE-060526-199
- Name
- two pore segment channel 1
- Symbol
- tpcn1 Nomenclature History
- Previous Names
-
- si:dkey-125i10.5
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable channel activity and identical protein binding activity. Predicted to be involved in calcium ion transmembrane transport; endocytosis involved in viral entry into host cell; and sodium ion transmembrane transport. Predicted to be located in early endosome membrane; endolysosome; and recycling endosome membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in endosome membrane and lysosomal membrane. Orthologous to human TPCN1 (two pore segment channel 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Rice et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ion transport domain | Two pore channel protein 1 | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BCG3 | InterPro | 810 | |||
| UniProtKB:A0A8N7TFG5 | InterPro | 811 | |||
| UniProtKB:A2BHL7 | InterPro | 805 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers