Gene
dpagt1
- ID
- ZDB-GENE-060526-18
- Name
- dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
- Symbol
- dpagt1 Nomenclature History
- Previous Names
-
- si:ch211-117m20.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity. Predicted to be involved in dolichyl diphosphate biosynthetic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ij and congenital myasthenic syndrome 13. Orthologous to human DPAGT1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from DeRossi et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Ij | Alliance | Congenital disorder of glycosylation, type Ij | 608093 |
| congenital myasthenic syndrome 13 | Alliance | Myasthenic syndrome, congenital, 13, with tubular aggregates | 614750 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DPAGT1, insertion domain | Glycosyl transferase, family 4 | UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase |
|---|---|---|---|---|
|
UniProtKB:A2BFS6
|
406 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dpagt1-201
(1)
|
Ensembl | 1,295 nt |
Interactions and Pathways
No data available
Plasmids
No data available