Gene
grp
- ID
- ZDB-GENE-060526-117
- Name
- gastrin-releasing peptide
- Symbol
- grp Nomenclature History
- Previous Names
-
- si:ch211-233a1.7 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable neuropeptide hormone activity. Predicted to be involved in neuropeptide signaling pathway and positive regulation of behavioral fear response. Predicted to be located in cytoplasmic vesicle and extracellular region. Predicted to be active in extracellular space. Is expressed in digestive system and preoptic area. Orthologous to human GRP (gastrin releasing peptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa23862 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000874 | Bombesin/neuromedin-B/ranatensin peptide family |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Bombesin/neuromedin-B/ranatensin peptide family |
|---|---|---|---|
| UniProtKB:A8E7H5 | InterPro | 153 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-233A1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001161350 (1) | |||
| Genomic | GenBank:BX248399 (1) | 158884 nt | ||
| Polypeptide | UniProtKB:A8E7H5 (1) | 153 aa |
- de Alba, G., Carrillo, S., Sánchez-Vázquez, F.J., López-Olmeda, J.F. (2022) Combined blue light and daily thermocycles enhance zebrafish growth and development. Journal of experimental zoology. Part A, Ecological and integrative physiology. 337(5):501-515
- Chen, S., Reichert, S., Singh, C., Oikonomou, G., Rihel, J., Prober, D.A. (2017) Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish. Neuron. 95(1):153-168.e6
- Dalmolin, C., Almeida, D.V., Figueiredo, M.A., Marins, L.F. (2015) Food intake and appetite control in a GH-transgenic zebrafish. Fish physiology and biochemistry. 41(5):1131-41
- Koven, W., and Schulte, P. (2012) The effect of fasting and refeeding on mRNA expression of PepT1 and gastrointestinal hormones regulating digestion and food intake in zebrafish (Danio rerio). Fish physiology and biochemistry. 38(6):1565-1575
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