ZFIN ID: ZDB-GENE-060519-9
Gene Name: THAP domain containing, apoptosis associated protein 1
Gene Symbol: thap1    Nomenclature History

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Previous Name: zgc:136597

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in cell cycle. Predicted to localize to nucleoplasm. Is expressed in head. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1).
Genome Resources: Alliance (1),  Gene:692315 (1),  Ensembl(GRCz11):ENSDARG00000059020 (2)
GENE EXPRESSION
All Expression Data: Table S9 from Zech et al., 2015
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH thap1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
torsion dystonia 6 Alliance Dystonia 6, torsion 602629
DISEASE ASSOCIATED WITH thap1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell cycle (more)
Cellular Component nucleoplasm (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM thap1 No data available
MARKER RELATIONSHIPS
thap1 Encodes: [cDNA] MGC:136597 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045284 (1) 949 nt
Genomic GenBank:FO904974 (1) 35850 nt
Select Tool
Polypeptide UniProtKB:Q1JPT7 (1) 225 aa
Sequence Information (all 11)
ORTHOLOGY for thap1 ( Chr: 5 )
CITATIONS (20)