Gene
cyp46a1.3
- ID
- ZDB-GENE-060519-40
- Name
- cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
- Symbol
- cyp46a1.3 Nomenclature History
- Previous Names
-
- zgc:136808 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cholesterol 24-hydroxylase | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q1JPS3
|
491 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp46a1.3-201
(1)
|
Ensembl | 1,476 nt |
Interactions and Pathways
No data available
Plasmids
No data available