Gene
cyp46a1.3
- ID
- ZDB-GENE-060519-40
- Name
- cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
- Symbol
- cyp46a1.3 Nomenclature History
- Previous Names
-
- zgc:136808 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum membrane; and postsynapse. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cholesterol 24-hydroxylase | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q1JPS3 | InterPro | 491 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp46a1.3-201
(1)
|
Ensembl | 1,476 nt |
Interactions and Pathways
No data available
Plasmids
No data available