ZFIN is now using GRCz12tu for Genomic Data
Gene
map4k6
- ID
- ZDB-GENE-060512-339
- Name
- mitogen-activated protein kinase kinase kinase kinase 6
- Symbol
- map4k6 Nomenclature History
- Previous Names
-
- zgc:136354 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001180 | Citron homology (CNH) domain |
| Family | IPR021160 | Mitogen-activated protein (MAP) kinase kinase kinase kinase |
| Family | IPR050629 | STE20/SPS1-related Proline-Alanine-rich Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Citron homology (CNH) domain | Mitogen-activated protein (MAP) kinase kinase kinase kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | STE20/SPS1-related Proline-Alanine-rich Kinase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q1JQ22 | InterPro | 889 | ||||||
| UniProtKB:A0A8M2B8G6 | InterPro | 899 | ||||||
| UniProtKB:A0A8M9PU24 | InterPro | 801 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map4k6-201
(1)
|
Ensembl | 3,342 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers