Gene
coq8b
- ID
- ZDB-GENE-060503-803
- Name
- coenzyme Q8B
- Symbol
- coq8b Nomenclature History
- Previous Names
-
- adck4 (1)
- si:dkey-114g7.2
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and kinase activity. Acts upstream of or within glomerular basement membrane development and podocyte development. Predicted to be located in cytosol; mitochondrion; and plasma membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 9. Orthologous to human COQ8B (coenzyme Q8B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Burkhalter et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ashraf et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrotic syndrome type 9 | Alliance | Nephrotic syndrome, type 9 | 615573 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ABC1 atypical kinase-like domain | ADCK3-like domain | Atypical kinase ADCK | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A3QJU3
|
624 | ||||
|
UniProtKB:A0A8M9NYH4
|
624 | ||||
|
UniProtKB:A0A8M9PIF5
|
656 |
Interactions and Pathways
No data available
Plasmids
No data available