Gene
rca2.2
- ID
- ZDB-GENE-060503-646
- Name
- regulator of complement activation group 2 gene 2
- Symbol
- rca2.2 Nomenclature History
- Previous Names
-
- zrc2 (1)
- si:dkey-78k11.2
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Is expressed in several structures, including eye; fin; gill; heart; and liver. Human ortholog(s) of this gene implicated in COVID-19; prostate cancer; and protein-losing enteropathy. Orthologous to human CD55 (CD55 molecule (Cromer blood group)) and C4BPA (complement component 4 binding protein alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wu et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rca2.2-201
(1)
|
Ensembl | 921 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-78K11 | ZFIN Curated Data |
1 - 1 of 1
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| Genomic | GenBank:AL845287 | 174301 nt |
No data available
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wu, J., Li, H., and Zhang, S. (2012) Regulator of complement activation (RCA) group 2 gene cluster in zebrafish: identification, expression, and evolution. Functional & integrative genomics. 12(2):367-377
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