Gene

slc26a4

ID
ZDB-GENE-060503-544
Name
solute carrier family 26 member 4
Symbol
slc26a4 Nomenclature History
Previous Names
  • si:dkey-31f5.9
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have anion transmembrane transporter activity. Involved in anion homeostasis; chloride transport; and response to salt stress. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in Pendred Syndrome; autosomal recessive nonsyndromic deafness 4; and goiter. Is expressed in several structures, including gill; heart; liver; muscle; and pleuroperitoneal region. Orthologous to human SLC26A4 (solute carrier family 26 member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc26a4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Deafness, autosomal recessive 4, with enlarged vestibular aqueduct 600791
Pendred syndrome 274600
Associated With slc26a4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018045 Sulphate anion transporter, conserved site
Domain IPR002645 STAS domain
Domain IPR011547 SLC26A/SulP transporter domain
Family IPR001902 SLC26A/SulP transporter
Homologous_superfamily IPR036513 STAS domain superfamily
Domain Details Per Protein
Protein Length SLC26A/SulP transporter SLC26A/SulP transporter domain STAS domain STAS domain superfamily Sulphate anion transporter, conserved site
UniProtKB:A0A8M6Z5Y9 779
UniProtKB:C8XTB7 760
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA slc26a4-201 (1) Ensembl 2280 nt
mRNA slc26a4-202 (1) Havana 2232 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations