Gene

slc12a10.3

ID

ZDB-GENE-060503-518

Name

solute carrier family 12 member 10, tandem duplicate 3

Symbol

slc12a10.3 Nomenclature History

Previous Names

si:dkey-114c3.3

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable sodium:potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in eye and kidney.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Wang et al., 2009

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc12a10.3 Human Ortholog

No data available

Associated With slc12a10.3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004841	Amino acid permease/ SLC12A domain
Domain	IPR018491	SLC12A transporter, C-terminal
Family	IPR002948	Thiazide-sensitive Na-K-Cl co-transporter
Family	IPR004842	SLC12A transporter family
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Amino acid permease/ SLC12A domain	P-type ATPase, transmembrane domain superfamily	SLC12A transporter, C-terminal	SLC12A transporter family	Thiazide-sensitive Na-K-Cl co-transporter
UniProtKB:B5DE35	InterPro	965
UniProtKB:A0A8M9QH36	InterPro	1001

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc12a10.3-201 (1) Ensembl	Ensembl	4,116 nt	Select Tool ZFIN BLAST
mRNA	slc12a10.3-202 (1) Ensembl	Ensembl	4,187 nt	Select Tool ZFIN BLAST
mRNA	slc12a10.3-203 (1) Ensembl	Ensembl	719 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations