Gene
gpr3
- ID
- ZDB-GENE-060503-489
- Name
- G protein-coupled receptor 3
- Symbol
- gpr3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Enables G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in brain; female organism; and testis. Orthologous to human GPR3 (G protein-coupled receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor 3/6/12 orphan | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
| UniProtKB:Q1LVV2 | InterPro | 326 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gpr186-201
(1)
|
Ensembl | 2,590 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-199G17 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001082915 (1) | 1140 nt | ||
| Genomic | GenBank:BX649384 (1) | 190998 nt | ||
| Polypeptide | UniProtKB:Q1LVV2 (1) | 326 aa |
- Hu, H., Long, Y., Song, G., Chen, S., Xu, Z., Li, Q., Wu, Z. (2023) Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish. International Journal of Molecular Sciences. 24(4):
- Li, Z., Jiang, B., Cao, B., Zhang, Z., Zhang, J., Li, J., Huang, Y., Wang, Y. (2021) Characterization of Four Orphan Receptors (GPR3, GPR6, GPR12 and GPR12L) in Chickens and Ducks and Regulation of GPR12 Expression in Ovarian Granulosa Cells by Progesterone. Genes. 12(4):
- Gans, I., Hartig, E.I., Zhu, S., Tilden, A.R., Hutchins, L.N., Maki, N.J., Graber, J.H., Coffman, J.A. (2020) Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity. Scientific Reports. 10:11415
- Newman, M., Hin, N., Pederson, S., Lardelli, M. (2019) Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular brain. 12:43
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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