ZFIN ID: ZDB-GENE-060503-452
Gene Name: argonaute RISC catalytic component 3b
Gene Symbol: ago3b    Nomenclature History

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Previous Names: Ago3b (1), eif2c3, eif2c3b, sb:eu332, si:dkey-3n22.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have endoribonuclease activity, cleaving miRNA-paired mRNA. Predicted to be involved in mRNA catabolic process and miRNA mediated inhibition of translation. Predicted to localize to P-body and RISC complex. Is expressed in several structures, including eye; fin; integument; pleuroperitoneal region; and somite. Orthologous to human AGO3 (argonaute RISC catalytic component 3).
Genome Resources: Alliance (1),  Gene:568159 (1),  Ensembl(GRCz11):ENSDARG00000063079 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu332]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ago3b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ago3b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process miRNA mediated inhibition of translation (more)
Cellular Component cytoplasm (more)
Molecular Function endoribonuclease activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ago3b-201 (1)    Ensembl 4368
ncRNA ago3b-002 (1)    Ensembl 670
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ago3b No data available
MARKER RELATIONSHIPS
ago3b Contained in: [BAC] DKEY-3N22 (1) (order this)
ago3b Encodes: [EST] eu332 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001160028 (1) 3062 nt
Genomic GenBank:BX005424 (1) 200523 nt Blast at MegaBLAST
Polypeptide UniProtKB:K4IKE9 (1) 867 aa
Sequence Information (all 15)
ORTHOLOGY for ago3b ( Chr: 19 )
CITATIONS (32)