Gene
adra1ab
- ID
- ZDB-GENE-060503-384
- Name
- adrenoceptor alpha 1Ab
- Symbol
- adra1ab Nomenclature History
- Previous Names
-
- si:ch211-136o4.3
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable alpha1-adrenergic receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; heroin dependence; and hypertension. Orthologous to human ADRA1A (adrenoceptor alpha 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PTZ0
|
431 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adra1ab-201
(1)
|
Ensembl | 1,282 nt | ||
| mRNA |
adra1ab-202
(1)
|
Ensembl | 2,067 nt |
Interactions and Pathways
No data available
Plasmids
No data available