Gene
tfpi2
- ID
- ZDB-GENE-060503-38
- Name
- tissue factor pathway inhibitor 2
- Symbol
- tfpi2 Nomenclature History
- Previous Names
-
- si:ch211-262k23.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Involved in several processes, including heart development; regulation of hemopoiesis; and sarcomere organization. Predicted to localize to extracellular space. Is expressed in brain; eye; heart; liver; and ovary. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Zhang et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
| Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
| Family | IPR008296 | Tissue factor pathway inhibitor-like |
| Family | IPR050098 | Kunitz-type Serine Protease Inhibitor |
| Homologous_superfamily | IPR036880 | Pancreatic trypsin inhibitor Kunitz domain superfamily |
Domain Details Per Protein
| Protein | Length | Kunitz-type Serine Protease Inhibitor | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Tissue factor pathway inhibitor-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q1WCN6
|
233 |
Interactions and Pathways
No data available
Plasmids
No data available