ZFIN is now using GRCz12tu for Genomic Data
Gene
sema4ab
- ID
- ZDB-GENE-060503-363
- Name
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
- Symbol
- sema4ab Nomenclature History
- Previous Names
-
- si:dkey-78d16.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; negative chemotaxis; and semaphorin-plexin signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 10 and retinitis pigmentosa 35. Orthologous to human SEMA4A (semaphorin 4A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Docampo-Seara et al., 2026
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 10 | Alliance | Cone-rod dystrophy 10 | 610283 |
| retinitis pigmentosa 35 | Alliance | Retinitis pigmentosa 35 | 610282 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sema4ab-201
(1)
|
Ensembl | 6,640 nt | ||
| mRNA |
sema4ab-202
(1)
|
Ensembl | 5,411 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers