kat2b

ID

ZDB-GENE-060503-207

Name

K(lysine) acetyltransferase 2B

Symbol

kat2b Nomenclature History

Previous Names

pcaf (1)
si:ch211-1j13.2
zgc:161980

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables histone H3K9 acetyltransferase activity. Involved in epigenetic regulation of gene expression; regulation of bone development; and regulation of cartilage development. Acts upstream of or within bone morphogenesis; heart development; and limb development. Predicted to be located in centrosome and nucleus. Predicted to be part of ATAC complex. Is expressed in fin; head; heart; and nervous system. Orthologous to human KAT2B (lysine acetyltransferase 2B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kat2b Human Ortholog

No data available

Associated With kat2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018359	Bromodomain, conserved site
Domain	IPR000182	GNAT domain
Domain	IPR001487	Bromodomain
Domain	IPR009464	PCAF, N-terminal
Family	IPR016376	Histone acetyltransferase GCN5/PCAF
Family	IPR037800	Histone acetyltransferase GCN5
Homologous_superfamily	IPR016181	Acyl-CoA N-acyltransferase
Homologous_superfamily	IPR036427	Bromodomain-like superfamily