Gene

dennd1b

ID
ZDB-GENE-060503-16
Name
DENN/MADD domain containing 1B
Symbol
dennd1b Nomenclature History
Previous Names
  • si:ch211-195i21.1 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have Rab guanyl-nucleotide exchange factor activity and phosphatidylinositol phosphate binding activity. Predicted to be involved in endocytic recycling and endocytosis. Predicted to localize to cytosol and intracellular membrane-bounded organelle. Is expressed in forebrain and hypothalamus. Orthologous to human DENND1B (DENN domain containing 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Yelin-Bekerman et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dennd1b Human Ortholog
No data available
Associated With dennd1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001194 cDENN domain
Domain IPR005112 dDENN domain
Domain IPR005113 uDENN domain
Domain IPR037516 Tripartite DENN domain
Family IPR040032 DENN domain-containing protein 1A/1B/1C
Homologous_superfamily IPR043153 DENN domain, C-terminal lobe
Domain Details Per Protein
Protein Length cDENN domain dDENN domain DENN domain-containing protein 1A/1B/1C DENN domain, C-terminal lobe Tripartite DENN domain uDENN domain
UniProtKB:A0A8M9PDK2 336
UniProtKB:A0A8M3B5N2 754
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dennd1b-201 (1) Ensembl 2,317 nt
mRNA dennd1b-202 (1) Ensembl 879 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations