ZFIN is now using GRCz12tu for Genomic Data
Gene
gpnmb
- ID
- ZDB-GENE-060503-106
- Name
- glycoprotein (transmembrane) nmb
- Symbol
- gpnmb Nomenclature History
- Previous Names
-
- si:ch211-155k24.6
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable integrin binding activity. Predicted to be involved in cell adhesion. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain and liver. Human ortholog(s) of this gene implicated in primary localized cutaneous amyloidosis 3. Orthologous to human GPNMB (glycoprotein nmb).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gupta et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary localized cutaneous amyloidosis 3 | Alliance | Amyloidosis, primary localized cutaneous, 3 | 617920 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin-like fold | PKAT, KLD domain | PKD- and KLD-Associated Transmembrane | PKD domain | PKD domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7TB94 | InterPro | 621 | |||||
| UniProtKB:E7F7J7 | InterPro | 627 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers