Gene
trim32
- ID
- ZDB-GENE-060428-1
- Name
- tripartite motif containing 32
- Symbol
- trim32 Nomenclature History
- Previous Names
-
- bbs11
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have zinc ion binding activity. Involved in several processes, including Kupffer's vesicle development; melanosome transport; and pronephric duct morphogenesis. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32).
- Genome Resources
-
- Alliance (1)
- Gene:562764 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yogev et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive limb-girdle muscular dystrophy type 2H | Alliance | Muscular dystrophy, limb-girdle, autosomal recessive 8 | 254110 |
| Bardet-Biedl syndrome 11 | Alliance | ?Bardet-Biedl syndrome 11 | 615988 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
| Domain | IPR047051 | TRIM32, B-box type 1 zinc finger |
| Homologous_superfamily | IPR011042 | Six-bladed beta-propeller, TolB-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Repeat | IPR001258 | NHL repeat |
Domain Details Per Protein
| Protein | Length | B-box-type zinc finger | NHL repeat | Six-bladed beta-propeller, TolB-like | TRIM32, B-box type 1 zinc finger | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IL45
|
|||||||||
|
UniProtKB:A8WGA9
|
663 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance