Gene

trim32

ID
ZDB-GENE-060428-1
Name
tripartite motif containing 32
Symbol
trim32 Nomenclature History
Previous Names
  • bbs11
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to have zinc ion binding activity. Involved in several processes, including Kupffer's vesicle development; melanosome transport; and pronephric duct morphogenesis. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 4 from Yogev et al., 2013
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trim32 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive limb-girdle muscular dystrophy type 2H Alliance Muscular dystrophy, limb-girdle, autosomal recessive 8 254110
Bardet-Biedl syndrome 11 Alliance ?Bardet-Biedl syndrome 11 615988
Associated With trim32 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR000315 B-box-type zinc finger
Domain IPR001841 Zinc finger, RING-type
Domain IPR027370 RING-type zinc-finger, LisH dimerisation motif
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Repeat IPR001258 NHL repeat
Repeat IPR013017 NHL repeat, subgroup
Domain Details Per Protein
Protein Length B-box-type zinc finger NHL repeat NHL repeat, subgroup RING-type zinc-finger, LisH dimerisation motif Six-bladed beta-propeller, TolB-like Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:A0A0R4IL45
UniProtKB:A8WGA9 663
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations