Gene

dab1b

ID
ZDB-GENE-060421-7958
Name
DAB adaptor protein 1b
Symbol
dab1b Nomenclature History
Previous Names
  • zgc:136547
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to be involved in lateral motor column neuron migration and ventral spinal cord development. Predicted to localize to cytoplasm. Is expressed in several structures, including blood; digestive system; immature eye; nervous system; and otic vesicle. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dab1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Spinocerebellar ataxia 37 615945
Associated With dab1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048559 Disabled homolog 1/2, sulfatide-binding motif
Domain IPR006020 PTB/PI domain
Domain IPR048561 Disabled, phosphotyrosine-binding domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Disabled homolog 1/2, sulfatide-binding motif Disabled, phosphotyrosine-binding domain PH-like domain superfamily PTB/PI domain
UniProtKB:A0A8M2BIU2 511
UniProtKB:A0A8M9PZW3 514
UniProtKB:Q1RM20 227
UniProtKB:A0A8M2BIE2 469
UniProtKB:F1R7Q8 440
UniProtKB:A0A8M2BIE0 520
UniProtKB:A0A8M2BIB2 478
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations