Gene

bco2b

ID

ZDB-GENE-060421-7448

Name

beta-carotene oxygenase 2b

Symbol

bco2b Nomenclature History

Previous Names

bcdo2 (1)
bcdo2a
bco2a (1)
wu:fk75b02
zgc:136769

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. Predicted to be active in mitochondrion. Is expressed in xanthophore. Orthologous to human BCO2 (beta-carotene oxygenase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Saunders et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bco2b Human Ortholog

No data available

Associated With bco2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004294	Carotenoid oxygenase
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily

Domain Details Per Protein

Protein	Length	Carotenoid oxygenase	Quinoprotein alcohol dehydrogenase-like superfamily
UniProtKB:Q1RLW1 InterPro	555

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	bco2b-201 (1) Ensembl	Ensembl		2,050 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations