Gene
bcl11aa
- ID
- ZDB-GENE-060421-4643
- Name
- BCL11 transcription factor A a
- Symbol
- bcl11aa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development. Predicted to be active in nucleus. Is expressed in dorsal telencephalon and telencephalon. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BCL11 transcription factor A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bagheri et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dias-Logan syndrome | 617101 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Developmental and Hematopoietic Transcription Factors | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:Q1RLR5
|
829 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bcl11aa-201
(1)
|
Ensembl | 9,615 nt | ||
| mRNA |
bcl11aa-202
(1)
|
Ensembl | 730 nt |
Interactions and Pathways
No data available
Plasmids
No data available