Gene
wnt5a
- ID
- ZDB-GENE-060328-3
- Name
- wingless-type MMTV integration site family, member 5a
- Symbol
- wnt5a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within pronephros development. Predicted to be active in extracellular space. Is expressed in brain; neural crest cell; ovarian follicle; pronephros; and tooth placode. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant Robinow syndrome 1 | Alliance | Robinow syndrome, autosomal dominant 1 | 180700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Wnt | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
| UniProtKB:A1BPR0 | InterPro | 374 | |||
| UniProtKB:A0AB32U0B6 | InterPro | 380 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available